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GLUC-012A
Glucagon-Like Peptide II, rat
His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Thr-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp
Size:0.5
P1(RMB):582
MW:3796.2
One letter sequence:HADGSFSDEMNTILDNLATRDFINWLIQTKITD
Molecular Formula:C166H256N44O56S1
Description:GLP-2 increases the stimulation of crypt cell proliferation and inhibition of enterocyte apoptosis, leading to hyperplasia of the small bowel villous epithelium. It also induces trophic effects in animal models of both small and large bowel injury such as experimental small bowel resection or chemically induced colitis. Besides stimulation of epithelial proliferation, GLP-2 acutely regulates gastric emptying and possesses rapid metabolic effects promoting the stimulation of intestinal hexose transport.
Literature Reference:
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