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GHRE-005A
(Des-octanoyl)-Ghrelin, human
Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Size:0.5
P1(RMB):460
MW:3244.7
One letter sequence:GSSFLSPEHQRVQQRKESKKPPAKLQPR
Molecular Formula:C141H235N47O41
Description:Small synthetic molecules, called growth-hormone secretagogues (GHSs), that stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). It has been demonstrated, however, to not possess the pituitaric and pancreatic endocrine activities of octanoylated ghrelin in humans.
Literature Reference:Family Literatures:M.Kojima et al., Nature, 402, 656(1999) \nC. Dieguez and F.F.Casanueva,Eur.J. Endocrinol., 142, 413(2000)
Cas:
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