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CASP-011B
Ac-YVAD-CHO
Ac-Tyr-Val-Ala-Asp-CHO
Size:5.0
P1(RMB):460
MW:492.5
One letter sequence:Ac-YVAD-CHO
Molecular Formula:C23H32N4O8
Description:Tetrapeptide aldehyde, a potent, specific, reversible inhibitor of caspase-1 (ICE) that displays a Ki of 0.2 ±0.1 nM for recombinant human caspase-1.
Literature Reference:N.A. Thornberry et al., Nature 356, 768 (1992); S.M. Molineaux et al., Proc. Natl. Acad. Sci. USA, 90, 1809 (1993); N.P.C. Walker et al., Cell, 78, 343 (1994)
Cas:[143313-51-3]