大奖888生化目录肽版块全新呈现,致力于打造全球最全面的多肽供应平台!我们专业的学术团队将时刻追踪最新最热的研究动向,帮助您发现实际需求,并以最高质量标准提供您所需要的产品。我们将我们将不定期更新产品列表,为您最大限度地节约科研时间,敬请广大客户朋友关注!
CANS-012A
Pep-1L-NOTA
H-Ala-Cys-Gly-Glu-Met-Gly-Trp-Val-Arg-Cys-Gly-Gly-Gly-Ser-C6-Lys-Lys(NOTA)-NH2 (trifluoroacetate salt)\r\n(Reduced Cys-H)
Size:1.0
P1(RMB):2380
MW:2023.36
One letter sequence:ACGEMGWVRCGGGS-C6-K-K(NOTA)-NH2
Molecular Formula:C84H139N27O25S3
Description:Metal chelating peptide Pep-1L-NOTA targets tumor-restricted receptor, IL13RA2, found to be present in some aggressive malignancies, specifically gliomas and malignant melanoma. Recent work has demonstrated that the copper-bound peptide selectively binds hIL13RA2-expressing tumors and validates its use in peptide-based PET imaging for cancer diagnostics.
Literature Reference:Sai, Kiran Kumar Solingapuram, et al. \"Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker.\" Oncotarget 5 (2017).
Cas: