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CANC-017A
p53 (17-26), FITC labeled
FITC-LC-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-NH2
Size:1
P1(RMB):869
MW:1753.1
One letter sequence:FITC-LC-ETFSDLWKLL-NH2
Molecular Formula:
Description: This is amino acids 17 to 26 fragment of p53, fluorescent labeled through an LC spacer. This peptide is the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that come into contact with the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development, FITC (Abs/Em=493 nm/517 nm)..\n
Literature Reference:Yu, G. et al. PNAS 103, 1227 (2006)\nWang, Y. et al. J. Biol. Chem. 281, 24803 (2006)\nKanovsky, M. et al. PNAS 98, 12438 (2001).
Cas: