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LYMK-002B
IFN-γ Antagonist
H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH
H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH
Size：1
P1(RMB)：2190
MW：2629.08
One letter sequence：AYC(Acm)RDGKIGPPKLDIRKEEKQI
Molecular Formula：C115H194N34O34S
Description：This peptide derived from the ligand binding site of the human γ-interferon (IFN-γ) receptor is an antagonist of human IFN-γ. It inhibited human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an approximate IC50 of 35 μM. Immobilized peptide specifically bound recombinant human IFN-γ Tyrosine substitution at residue 121 allowed facile quantification and conjugation of the peptide.
Literature Reference：G.F.Seelig et al., J. Biol. Chem., 270, 9241 (1995)\n
Cas：158040-83-6
P1(RMB)：2190
MW：2629.08
One letter sequence：AYC(Acm)RDGKIGPPKLDIRKEEKQI
Molecular Formula：C115H194N34O34S
Description：This peptide derived from the ligand binding site of the human γ-interferon (IFN-γ) receptor is an antagonist of human IFN-γ. It inhibited human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an approximate IC50 of 35 μM. Immobilized peptide specifically bound recombinant human IFN-γ Tyrosine substitution at residue 121 allowed facile quantification and conjugation of the peptide.
Literature Reference：G.F.Seelig et al., J. Biol. Chem., 270, 9241 (1995)\n
Cas：158040-83-6
