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LYMK-001B
IFN-α Receptor Recognition Peptide 1 (IRRP1)\n
H-Cys-Leu-Lys-Asp-Arg-His-Asp-OH
Size:5
P1(RMB):6070
MW:886
One letter sequence:CLKDRHD
Molecular Formula:C35H59N13O12S
Description:The peptide IRRP1 is derived from a consensus IFN-α sequence and corresponds to a putative receptor recognition domain of IFN-α. The binding capacity of cells for IFN-αs was increased in the presence of IRRP1. Increased receptor occupancy resulted in increased phosphorylation-activation of the transcription factor ISGF3 and enhanced antiviral activity.
Literature Reference:E.N.Fish, FEBS Lett., 365, 87 (1995)\n
Cas:153840-64-3