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AAV2-001A
Adeno-Associated Virus Epitope 2 (AAV2)
Val-Pro-Gln-Tyr-Gly-Tyr-Leu-Thr-Leu
Val-Pro-Gln-Tyr-Gly-Tyr-Leu-Thr-Leu
Size：1
P1(RMB)：278
MW：1053.2
One letter sequence：VPQYGYLTL-OH
Molecular Formula：N/A
Description： This peptide is the CD8 T cell epitope from adeno-associated virus 2 (AAV2) capsid. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.
Literature Reference：Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006)\nMingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007)\nWang, L. et al. Therapy. 18, 185 (2007).
Cas：N/A
P1(RMB)：278
MW：1053.2
One letter sequence：VPQYGYLTL-OH
Molecular Formula：N/A
Description： This peptide is the CD8 T cell epitope from adeno-associated virus 2 (AAV2) capsid. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.
Literature Reference：Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006)\nMingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007)\nWang, L. et al. Therapy. 18, 185 (2007).
Cas：N/A
