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SUBS-001A
Substance P
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Size:5.0
P1(RMB):276
MW:1347.7
One letter sequence:RPKPQQFFGLM-NH2
Molecular Formula:C63H98N18O13S1
Description:This neuropeptide was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. It contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, it causes a neurogenic inflammatory response, including mast cell degranulation.
Literature Reference:A.I. Roberts et al., Cell Immunol., 141, 457 (1992)
Cas:
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